Article
Significance of HBV DNA levels at 12 weeks of telbivudine treatment and the 3 years treatment outcome.
Journal of hepatology - 1 Sept 2011
Seto Wai-Kay, Lai Ching-Lung, Fung James, Wong Danny Ka-Ho, Yuen John Chi-Hang, Hung Ivan Fan-Ngai, Yuen Man-Fung
Abstract excerpt
BACKGROUND & AIMS: The significance of early HBV DNA suppression during telbivudine treatment in predicting long-term outcomes needs further investigation. METHODS: We determined the cumulative rates of HBeAg seroconversion, ALT normalization, HBV DNA suppression (<12IU/ml) and telbivudine resistant mutations (using the highly sensitive line probe assay) for 117 treatment-native chronic hepatitis B (CHB) patients...
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