Article
Tag SNPs detect association of the CYP1B1 gene with primary open angle glaucoma.
Molecular vision - 4 Nov 2010
Burdon Kathryn P, Hewitt Alex W, Mackey David A, Mitchell Paul, Craig Jamie E
Abstract excerpt
PURPOSE: The cytochrome p450 family 1 subfamily B (CYP1B1) gene is a well known cause of autosomal recessive primary congenital glaucoma. It has also been postulated as a modifier of disease severity in primary open angle glaucoma (POAG), particularly in juvenile onset families. However, the role of common variation in the gene in relation to POAG has not been thoroughly explored. METHODS: Seven tag single...
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