Article
A sequence-specific DNA-binding protein that activates fushi tarazu segmentation gene expression.
Genes & development - 1 Apr 1990
Ueda H, Sonoda S, Brown J L, Scott M P, Wu C
Abstract excerpt
The Drosophila segmentation gene fushi tarazu (ftz) is expressed at the cellular blastoderm stage in a pattern of seven transverse stripes; the stripes lie out of register with the segmental primordia, spanning alternate segmental boundaries. The zebra element, a 740-bp DNA sequence upstream of the ftz translational start, directs striped expression of lacZ when introduced into the fly genome. We have purified to...
Topics
- Animals
- Base Sequence
- Blotting, Western
- DNA-Binding Proteins
- Drosophila Proteins
- Drosophila melanogaster
- Fushi Tarazu Transcription Factors
- Gene Expression Regulation
- Homeodomain Proteins
- Immunohistochemistry