Article
Comparative proteomic analysis of biofilm and planktonic cells of Neisseria meningitidis.
Proteomics - 1 Dec 2010
van Alen Tessa, Claus Heike, Zahedi René P, Groh Janos, Blazyca Heinrich, Lappann Martin, Sickmann Albert, Vogel Ulrich
Abstract excerpt
Neisseria meningitidis is a commensal of the human nasopharynx occasionally causing invasive disease. In vitro biofilms have been employed to model meningococcal carriage. A proteomic analysis of meningococcal biofilms was conducted and metabolic changes related to oxygen and nutrient limitation and upregulation of proteins involved in ROS defense were observed. The upregulated MntC which protects against ROS was...
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