Article
Expression of multiple membrane-associated phospholipase A1 beta transcript variants and lysophosphatidic acid receptors in Ewing tumor cells.
Molecular biology reports - 1 Oct 2011
Schmiedel Benjamin Joachim, Hutter Christoph, Hesse Manuela, Staege Martin Sebastian
Abstract excerpt
The prognosis for patients with advanced stages of Ewing family tumors (EFT) is very poor. EFT express high levels of phosphatidic acid specific membrane-associated phospholipase A1 beta (lipase I, LIPI). LIPI is a cancer/testis antigen and the high tumor specificity suggests that LIPI might be a...
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