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Article

Endometriosis-Associated Ovarian Cancer: The Origin and Targeted Therapy

24 Jun 2020

Abstract excerpt

Endometrial cysts (ECs) are thought to be the origin of endometriosis-associated ovarian cancer (EAOC). A hypothesis that the oxidative stress of iron in cysts causes "malignant transformation of ECs" has been proposed, but this has not been verified. Several population-based studies showed that endometriosis was a risk factor but did not reflect the "malignant transformation of ECs". A review showed that most...

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PMID: 32599890
DOI: 10.3390/cancers12061676

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