Human genotype-to-phenotype predictions: Boosting accuracy with nonlinear models.

Abstract excerpt

Genotype-to-phenotype prediction is a central problem of human genetics. In recent years, it has become possible to construct complex predictive models for phenotypes, thanks to the availability of large genome data sets as well as efficient and scalable machine learning tools. In this paper, we make a threefold contribution to this problem. First, we ask if state-of-the-art nonlinear predictive models, such as...

Topics

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• Genome-Wide Association Study
• Genotype
• Models, Genetic
• Nonlinear Dynamics
• Phenotype