Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Metallothioneins are required for formation of cross-adaptation response to neurobehavioral toxicity from lead and mercury exposure in nematodes.

PloS one - 18 Nov 2010

Ye Boping, Rui Qi, Wu Qiuli, Wang Dayong

Abstract excerpt

Metallothioneins (MTs) are small, cysteine-rich polypeptides, but the role of MTs in inducing the formation of adaptive response is still largely unknown. We investigated the roles of metallothionein genes (mtl-1 and mtl-2) in the formation of cross-adaptation response to neurobehavioral toxicity from metal exposure in Caenorhabditis elegans. Pre-treatment with mild heat-shock at L2-larva stage effectively...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animals, Genetically Modified
Share to Caenorhabditis elegans Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Heat-Shock Response

Share to Hot Temperature

Share to Mercury

Share to Metallothionein

Share to Motor Activity

Source

Open in PubMed Open full text

Identifiers

PMID: 21124968
DOI: 10.1371/journal.pone.0014052
PMCID: PMC2987793

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Metallothioneins are required for formation of cross-adaptation response to neurobehavioral toxicity from lead and mercury exposure in nematodes.PMID 21124968Read ↗

Transferable properties of multi-biological toxicity caused by cobalt exposure in Caenorhabditis elegans.Semantic proximity Read ↗

C. elegans metallothioneins: new insights into the phenotypic effects of cadmium toxicosis.Semantic proximity Read ↗

Multi-biological defects caused by lead exposure exhibit transferable properties from exposed parents to their progeny in Caenorhabditis elegans.Semantic proximity Read ↗

Combined effect of temperature and zinc on Caenorhabditis elegans wild type and daf-21 mutant strains.Semantic proximity Read ↗

Genetic evidence behind the Cd resistance of wild Metaphire californica: The global RNA regulation rather than specific mutation of well-known gene.Semantic proximity Read ↗

Detoxification of multiple heavy metals by a half-molecule ABC transporter, HMT-1, and coelomocytes of Caenorhabditis elegans.Semantic proximity Read ↗

Molecular characterization of numr-1 and numr-2: genes that increase both resistance to metal-induced stress and lifespan in Caenorhabditis elegans.Semantic proximity Read ↗

Biosafety assessment of titanium dioxide nanoparticles in acutely exposed nematode Caenorhabditis elegans with mutations of genes required for oxidative stress or stress response.Semantic proximity Read ↗

Overexpression of metal-responsive transcription factor (MTF-1) in Drosophila melanogaster ameliorates life-span reductions associated with oxidative stress and metal toxicity.Semantic proximity Read ↗

Nickel sulfate induces numerous defects in Caenorhabditis elegans that can also be transferred to progeny.Semantic proximity Read ↗

Stress-induced phenocopy of C. elegans defines functional steps of sensory organ differentiation.Semantic proximity Read ↗

Role of MTL-1, MTL-2, and CDR-1 in mediating cadmium sensitivity in Caenorhabditis elegans.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.