Article
Chalcones as novel influenza A (H1N1) neuraminidase inhibitors from Glycyrrhiza inflata.
Bioorganic & medicinal chemistry letters - 1 Jan 2011
Dao Trong Tuan, Nguyen Phi Hung, Lee Hong Sik, Kim Eunhee, Park Junsoo, Lim Seong Il, Oh Won Keun
Abstract excerpt
The emergence of highly pathogenic influenza A virus strains, such as the new H1N1 swine influenza (novel influenza), represents a serious threat to global human health. During our course of an anti-influenza screening program on natural products, one new licochalcone G (1) and seven known (2-8) chalcones were isolated as active principles from the acetone extract of Glycyrrhiza inflata. Compounds 3 and 6 without...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
