Article
The correlation between COMT gene polymorphism and early cerebral vasospasm after subarachnoid hemorrhage.
Acta neurochirurgica. Supplement - 1 Jan 2011
He Zhaohui, Sun Xiaochuan, Guo Zongduo, Zhang John H
Abstract excerpt
BACKGROUND: The individual difference of cerebral vasospasm (CVS) degree after subarachnoid hemorrhage (SAH) is common in clinic observation. Numerous studies have found that early CVS after SAH is associated with derangements in catecholamine (CA) metabolism. Catechol-O-methyltransferase (COMT) is a key rate-limiting enzyme in the degradation of CA. In this study, we investigate the correlation between COMT gene...
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