Article
Cystic fibrosis Δf508 mutation screening in Brazilian women with altered fertility.
Molecular biology reports - 1 Oct 2011
Brunoro G V F, Wolfgramm E V, Louro I D, Degasperi I I, Busatto V C W, Perrone A M S, Batitucci M C P
Abstract excerpt
Cystic Fibrosis (CF) is an autosomal recessive disease, caused by mutations in the Cystic Fibrosis Transmembrane Regulator gene (CFTR). The most frequent mutation in CF is ΔF508. The disease is clinically characterized by elevated concentrations of sweat chlorides and abnormally thick mucus. It affects organs such as lung, pancreas, gastrointestinal and reproductive tract. Women with CF commonly present delayed...
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