Article
The functional polymorphism in monocyte chemoattractant protein-1 gene increases susceptibility to gastric cancer.
Medical oncology (Northwood, London, England) - 1 Dec 2011
Gu Haijuan, Ni Meixin, Guo Xiaohong, Feng Ping, Xu Yanyan, Gu Xiang, Yang Li, Wang Bin
Abstract excerpt
Monocyte chemoattractant protein-1 (MCP-1, CCL2) has been suggested to be associated with gastric cancer. We investigated whether the functional single nucleotide polymorphism A-2518G in CCL2 gene influenced susceptibility to gastric cancer. The CCL2 genotypes were determined using polymerase chain reaction-restriction fragment length polymorphism in 1,216 individuals (608 gastric cancer patients and 608 age- and...
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