Article
Adult endothelial progenitor cells retain hematopoiesis potential.
Transplantation proceedings - 1 Nov 2010
Chen C, Zeng L, Ding S, Xu K
Abstract excerpt
Hematopoietic stem cells (HSCs) are derived from endothelium in the aortic-gonado-mesonephric (AGM) region during embryogenesis. But little is known about whether endothelial progenitor cells (EPCs) retain hematopoiesis potential after birth. In this study, we isolated adult EPCs from the bone marrow of C57BL/6 mice and identified them with an endothelial functional assay and by the CD31(+) CD133(+) CD45(-/dim)...
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