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Article

Retention of progenitor cell phenotype in otospheres from guinea pig and mouse cochlea.

Journal of translational medicine - 18 Nov 2010

Oiticica Jeanne, Barboza-Junior Luiz Carlos M, Batissoco Ana Carla, Lezirovitz Karina, Mingroni-Netto Regina C, Haddad Luciana A, Bento Ricardo F

Abstract excerpt

BACKGROUND: Culturing otospheres from dissociated organ of Corti is an appropriate starting point aiming at the development of cell therapy for hair cell loss. Although guinea pigs have been widely used as an excellent experimental model for studying the biology of the inner ear, the mouse cochlea has been more suitable for yielding otospheres in vitro. The aim of this study was to compare conditions and outcomes...

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Source

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Identifiers

PMID: 21087511
DOI: 10.1186/1479-5876-8-119
PMCID: PMC3001427

Genes

EGF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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