Article
Short communication: identification of a novel HIV type 1 subtype H/J recombinant in Canada with discordant HIV viral load (RNA) values in three different commercial assays.
AIDS research and human retroviruses - 1 Nov 2007
Kim John E, Beckthold Brenda, Chen Zhaoxia, Mihowich Jennifer, Malloch Laurie, Gill Michael John
Abstract excerpt
The presence of HIV-1 non-B subtypes is increasing worldwide. This poses challenges to commercial diagnostic and viral load (RNA) monitoring tests that are predominantly based on HIV-1 subtype B strains. Based on phylogenetic analysis of the gag, pol, and env gene regions, we describe the first HIV-1 H/J recombinant in Canada that presented divergent viral load values. DNA sequence analysis of the gag gene region...
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