Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

β-globin gene haplotypes linked with the Hb D-Punjab [β121(GH4)Glu→Gln, GAA>CAA] mutation in eastern India.

Hemoglobin - 1 Jan 2010

Patel Dilip K, Mashon Ranjeet S, Patel Siris, Dash Preetinanda M, Das Bhabani S

Abstract excerpt

Hb D-Punjab [β121(GH4)Glu→Gln] is prevalent in the northern states of the Indian subcontinent. Due to inadequate data from Asian countries, the origin and spread of the Hb D-Punjab mutation are uncertain. In a study of sickle cell hemoglobinopathies, we detected the Hb D-Punjab mutation in 25 subjects from 11 unrelated Agharia families. Twelve cases were Hb S [β6(A3)Glu→Val]/Hb D-Punjab compound heterozygotes and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to beta-Globins
Share to DNA Mutational Analysis

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Family Health

Share to Genotype

Share to Haplotypes

Share to Hemoglobins, Abnormal

Share to Mutation, Missense

Source

Identifiers

PMID: 21077760
DOI: 10.3109/01676830.2010.525900

Genes

GAA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

β-globin gene haplotypes linked with the Hb D-Punjab [β121(GH4)Glu→Gln, GAA>CAA] mutation in eastern India.PMID 21077760Read ↗

Coexistence of rare variant HbD Punjab [α2β2(121(Glu→Gln))] and alpha 3.7 kb deletion in a young boy of Hindu family in West Bengal, India.Semantic proximity Read ↗

Hemoglobin D-Punjab: origin, distribution and laboratory diagnosisSemantic proximity Read ↗

The molecular basis of beta thalassaemia in Punjabi and Maharashtran Indians includes a multilocus aetiology involving triplicated alpha-globin loci.Semantic proximity Read ↗

Co-inheritance of Hb D-Punjab (codon 121; GAA-->CAA) and beta (0) -thalassemia (IVS-II-1;G-->A).Semantic proximity Read ↗

Phenotypic Diversity of Sickle Cell Disease in Patients with a Double Heterozygosity for Hb S and Hb D-Punjab.Semantic proximity Read ↗

Hb D-Agri [beta9(A6)Ser --> Tyr;beta121(GH4)Glu --> Gln]: a new Indian hemoglobin variant with two amino acid substitutions in the same beta chain.Semantic proximity Read ↗

Nucleotide -88 (C-T) promoter mutation is a common beta-thalassemia mutation in the Jat Sikhs of Punjab, India.Semantic proximity Read ↗

Clinical and hematological presentation among Indian patients with common hemoglobin variants.Semantic proximity Read ↗

Missing Hb Q-India Peak in a Triple-Heterozygous Patient with Hb D-Punjab/Hb Q-India/β-Thalassemia Trait.Semantic proximity Read ↗

[The association of beta zero-thalassemia and Hb D Punjab in a family of Indian origin. The second case reported in Spain].Semantic proximity Read ↗

[Molecular identification of Hemoglobin D Punjab in cases detected in two families].Semantic proximity Read ↗

Abnormal hemoglobins in the Silk Road region of China.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.