Article
XerCD-mediated site-specific recombination leads to loss of the 57-kilobase gonococcal genetic island.
Journal of bacteriology - 1 Jan 2011
Domínguez Nadia M, Hackett Kathleen T, Dillard Joseph P
Abstract excerpt
Most strains of Neisseria gonorrhoeae carry the 57-kb gonococcal genetic island (GGI), as do a few strains of Neisseria meningitidis. The GGI is inserted into the chromosome at the dif site (difA) and is flanked by a partial repeat of the dif site (difB). Since dif is a sequence recognized by the site-specific recombinases XerC and XerD and the GGI shows evidence of horizontal acquisition, we hypothesized that...
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