Article
Diabetic retinopathy: Validation study of ALR2, RAGE, iNOS and TNFB gene variants in a south Indian cohort.
Ophthalmic genetics - 1 Dec 2010
Uthra Satagopan, Raman Rajiv, Mukesh Bickol N, Rajkumar Samuel A, Kumari Padmaja, Lakshmipathy Praveena, Gnanamoorthy Perumal, Sharma Tarun, McCarty Catherine A, Kumaramanickavel Govindasamy
Abstract excerpt
PURPOSE: We previously reported the association of the Z-2 allele of the promoter dinucleotide repeat in the Aldose reductase (ALR2) gene, the (CCTTT)₁₅ allele in the promoter of inductible nitric oxide synthase (iNOS) gene, and the (GT)₁₃ promoter polymorphism in the tumor necrosis factor β (TNFB) gene with an increased risk for diabetic retinopathy (DR), and the Gly82Ser polymorphism in the receptor for...
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