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Article

One hundred years of pleiotropy: a retrospective.

Genetics - 1 Nov 2010

Stearns Frank W

Abstract excerpt

Pleiotropy is defined as the phenomenon in which a single locus affects two or more distinct phenotypic traits. The term was formally introduced into the literature by the German geneticist Ludwig Plate in 1910, 100 years ago. Pleiotropy has had an important influence on the fields of physiological and medical genetics as well as on evolutionary biology. Different approaches to the study of pleiotropy have led to...

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Identifiers

PMID: 21062962
DOI: 10.1534/genetics.110.122549
PMCID: PMC2975297

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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