Article
Combined analysis of estrogen receptor beta-1 and progesterone receptor expression identifies lung cancer patients with poor outcome.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Jan 2011
Stabile Laura P, Dacic Sanja, Land Stephanie R, Lenzner Diana E, Dhir Rajiv, Acquafondata Marie, Landreneau Rodney J, Grandis Jennifer R, Siegfried Jill M
Abstract excerpt
PURPOSE: Steroid hormones and growth factors affect lung cancer, and it is possible they act in concert to influence patient outcome. EXPERIMENTAL DESIGN: Primary lung tumors and normal lung tissue were analyzed for expression and localization of estrogen receptor α and β-1 (ERα and ERβ), aromatase, progesterone receptor (PR), and epidermal growth factor receptor (EGFR). RESULTS: Tumors expressed higher levels of...
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