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Article

Actin depolymerizing factors cofilin1 and destrin are required for ureteric bud branching morphogenesis.

PLoS genetics - 28 Oct 2010

Kuure Satu, Cebrian Cristina, Machingo Quentin, Lu Benson C, Chi Xuan, Hyink Deborah, D'Agati Vivette, Gurniak Christine, Witke Walter, Costantini Frank

Abstract excerpt

The actin depolymerizing factors (ADFs) play important roles in several cellular processes that require cytoskeletal rearrangements, such as cell migration, but little is known about the in vivo functions of ADFs in developmental events like branching morphogenesis. While the molecular control of ureteric bud (UB) branching during kidney development has been extensively studied, the detailed cellular events...

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Identifiers

PMID: 21060807
DOI: 10.1371/journal.pgen.1001176
PMCID: PMC2965756

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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