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Article

Advances in translational research in neuro-oncology.

Archives of neurology - 1 Mar 2011

Fueyo Juan, Gomez-Manzano Candelaria, Yung W K Alfred

Abstract excerpt

During the last decade, we have witnessed several key advances in the field of neuro-oncology. First, there were conceptual advances in the molecular and cell biology of malignant gliomas including the discovery in 2004 of brain tumor stem cells. Second, the Cancer Genome Atlas project has been extremely useful in the discovery of new molecular markers, including mutations in the IDH1 gene, and has led to a new...

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Identifiers

PMID: 21059986
DOI: 10.1001/archneurol.2010.293
PMCID: PMC3109723

Genes

IDH1

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