High expression of the immature laminin receptor protein correlates with mutated IGVH status and predicts a favorable prognosis in chronic lymphocytic leukemia.

doi:10.1016/j.leukres.2010.10.002

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High expression of the immature laminin receptor protein correlates with mutated IGVH status and predicts a favorable prognosis in chronic lymphocytic leukemia.

Leukemia research - 1 Jun 2011

Friedrichs Birte, Siegel Sandra, Reimer Rudolph, Barsoum Adel, Coggin Joseph, Kabelitz Dieter, Heidorn Klaus, Schulte Christoph, Schmitz Norbert, Zeis Matthias

Abstract excerpt

The immature laminin receptor (iLR) is a tumor-associated antigen. We analyzed the expression of iLR on malignant B cells of 134 unselected patient samples with CLL and hypothesized that iLR expression would have prognostic significance due to a differential expression pattern. High ILR expressio...

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High expression of the immature laminin receptor protein correlates with mutated IGVH status and predicts a favorable prognosis in chronic lymphocytic leukemia.

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