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Measuring the efficacy of anti-malarial drugs in vivo: quantitative PCR measurement of parasite clearance

5 Nov 2010

Abstract excerpt

BACKGROUND: Artemisinin-based combination therapy, currently considered the therapy of choice for uncomplicated Plasmodium falciparum malaria in endemic countries, may be under threat from newly emerging parasite resistance to the artemisinin family of drugs. Studies in Southeast Asia suggest some patients exhibit an extended parasite clearance time in the three days immediately following treatment with...

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PMID: 21054863
DOI: 10.1186/1475-2875-9-312

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