Nervous system tumors associated with familial tumor syndromes.

doi:10.1097/WCO.0b013e3283405b5f

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Article

Nervous system tumors associated with familial tumor syndromes.

Current opinion in neurology - 1 Dec 2010

Ohgaki Hiroko, Kim Young-Ho, Steinbach Joachim P

Abstract excerpt

PURPOSE OF REVIEW: There are several well-characterized hereditary syndromes that predispose to the development of tumors of the nervous system, and that result from germline mutations in high-penetrance genes. In this review, we provide a brief overview of these syndromes. RECENT FINDINGS: The elucidation of the molecular basis of hereditary syndromes has greatly contributed to our understanding of the...

Topics

Child
Genetic Diseases, Inborn
Genetic Predisposition to Disease
Humans
Medulloblastoma
Nervous System Neoplasms
Signal Transduction
Syndrome
Tuberous Sclerosis

Source

Open in PubMed

Identifiers

PMID: 21042217
DOI: 10.1097/WCO.0b013e3283405b5f

Genes

PTCH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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