Article
Neurooncology of familial cancer syndromes.
Journal of child neurology - 1 Dec 2009
Hottinger Andreas F, Khakoo Yasmin
Abstract excerpt
The majority of tumors of the nervous system are sporadic. However, a subset of patients with tumors and their families are predisposed to developing cancers of the central nervous system and other organs because of a germline mutation. In the last decade, many of the genes responsible for these typically autosomal dominant familial tumor syndromes have been identified. Additionally, our understanding of the...
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