Article
Pathological Features of Tumors of the Nervous System in Hereditary Cancer Predisposition Syndromes: A Review.
Neurosurgery - 16 Aug 2021
Tadros Saber, Kondrashov Aleksei, Namagiri Sriya, Chowdhury Ashis, Banasavadi-Siddegowda Yeshavanth Kumar, Ray-Chaudhury Abhik
Abstract excerpt
Hereditary cancer predisposition syndromes (HCS) become more recognizable as the knowledge about them expands, and genetic testing becomes more affordable. In this review, we discussed the known HCS that predispose to central and peripheral nervous system tumors. Different genetic phenomena were highlighted, and the important cellular biological alterations were summarized. Genetic mosaicism and germline...
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