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Article

Prolonged shedding of amantadine- and oseltamivir-resistant influenza A(H3N2) virus with dual mutations in an immunocompromised infant.

Antiviral therapy - 1 Jan 2010

Ruiz-Carrascoso Guillermo, Casas Inmaculada, Pozo Francisco, González-Vincent Marta, Pérez-Breña Pilar

Abstract excerpt

In this study, we report a case of multidrug-resistant influenza A(H3N2) virus isolated from an immunosuppressed patient with prolonged viral shedding. We also describe the genetic characterization of the haemagglutinin, neuraminidase and M2 influenza genes. The virus contained the substitutions E119V in neuraminidase and V27A in M2, which produce resistance to oseltamivir and adamantanes, respectively. This is...

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Identifiers

PMID: 21041923
DOI: 10.3851/IMP1657

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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