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Adhesive Activity of the Haemophilus Cryptic Genospecies Cha Autotransporter Is Modulated by Variation in Tandem Peptide Repeats

30 Oct 2010

Abstract excerpt

The Haemophilus cryptic genospecies is an important cause of maternal genital tract and neonatal systemic infections and initiates infection by colonizing the genital or respiratory epithelium. In recent work, we identified a unique Haemophilus cryptic genospecies protein called Cha, which mediates efficient adherence to genital and respiratory epithelia. The Cha adhesin belongs to the trimeric autotransporter...

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PMID: 21037000
DOI: 10.1128/jb.00933-10

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