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Article

The role of active site residues in the oxidant specificity of the Orp1 thiol peroxidase.

Biochemical and biophysical research communications - 3 Dec 2010

Takanishi Christina L, Ma Li-Hua, Wood Matthew J

Abstract excerpt

In this study we investigated the role of active site residues in the peroxidase activity of Orp1 (GPx3) using three different peroxide substrates. Using a structural homology model of the reduced form of Orp1, we identified Asn126 and Phe127 as evolutionarily conserved residues that line the bac...

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Identifiers

PMID: 21036150
DOI: 10.1016/j.bbrc.2010.10.109

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21036150-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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