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Article

High dietary intake of retinol leads to bone marrow hypoxia and diaphyseal endosteal mineralization in rats.

Bone - 1 Mar 2011

Lind Thomas, Lind P Monica, Jacobson Annica, Hu Lijuan, Sundqvist Anders, Risteli Juha, Yebra-Rodriguez Africa, Larsson Sune, Rodriguez-Navarro Alejandro, Andersson Göran, Melhus Håkan

Abstract excerpt

Vitamin A (retinol) is the only molecule known to induce spontaneous fractures in laboratory animals and we have identified retinol as a risk factor for fracture in humans. Since subsequent observational studies in humans and old animal data both show that high retinol intake appears to only have...

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Identifiers

PMID: 21035577
DOI: 10.1016/j.bone.2010.10.169

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21035577-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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