Association between CAG repeat length in the PPP2R2B gene and Alzheimer disease in the Japanese population.

doi:10.1016/j.neulet.2010.10.055

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Association between CAG repeat length in the PPP2R2B gene and Alzheimer disease in the Japanese population.

Neuroscience letters - 10 Jan 2011

Kimura Ryo, Morihara Takashi, Kudo Takashi, Kamino Kouzin, Takeda Masatoshi

Abstract excerpt

We analyzed the association between PPP2R2B gene CAG repeat length and Alzheimer disease (AD) susceptibility in the Japanese population. Blood samples were collected from 218 late-onset AD patients and 86 controls. DNA fragments containing the target CAG repeat region were amplified using polymerase chain reaction (PCR). PCR products were sequenced using ABI PRISM 310 genetic analyzer. The mean CAG repeat length...

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Association between CAG repeat length in the PPP2R2B gene and Alzheimer disease in the Japanese population.

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