Article
[Anti-inflammatory action of lipid-bound apoA-I cysteine mutants].
Zhonghua yi xue za zhi - 22 Jun 2010
Wang Yun-long, Lu Shu-lai, Niu Zhao-he, Miao Zhi-min, Li Xin-de, Zhang Yan-qiu, Li Chang-gui, Chen Bao-sheng
Abstract excerpt
OBJECTIVE: To determine the anti-inflammatory functions of different cysteine mutants of apolipoprotein A-I recombinant HDLs. METHODS: The recombinant HDLs (named rHDL52, rHDL107, rHDL173, rHDLwt) were reconstituted by mixing wild types or their mutants with dipalmitoyl phosphatidylcholine. And the in vivo effects on lipopolysaccharide (LPS)-induced endotoxemia were examined in mice. The plasma levels of plasma...
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