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Article

Transition from positive to neutral in mutation fixation along with continuing rising fitness in thermal adaptive evolution.

PLoS genetics - 21 Oct 2010

Kishimoto Toshihiko, Iijima Leo, Tatsumi Makoto, Ono Naoaki, Oyake Ayana, Hashimoto Tomomi, Matsuo Moe, Okubo Masato, Suzuki Shingo, Mori Kotaro, Kashiwagi Akiko, Furusawa Chikara, Ying Bei-Wen, Yomo Tetsuya

Abstract excerpt

It remains to be determined experimentally whether increasing fitness is related to positive selection, while stationary fitness is related to neutral evolution. Long-term laboratory evolution in Escherichia coli was performed under conditions of thermal stress under defined laboratory conditions. The complete cell growth data showed common continuous fitness recovery to every 2°C or 4°C stepwise temperature...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20975944
DOI: 10.1371/journal.pgen.1001164
PMCID: PMC2958811

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Source receipt: pubmed, retrieved 7 Sept 2026.

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