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Article

Testing mutual exclusivity of ETS rearranged prostate cancer

25 Oct 2010

Abstract excerpt

Prostate cancer is a clinically heterogeneous and multifocal disease. More than 80% of patients with prostate cancer harbor multiple geographically discrete cancer foci at the time of diagnosis. Emerging data suggest that these foci are molecularly distinct consistent with the hypothesis that they arise as independent clones. One of the strongest arguments is the heterogeneity observed in the status of E26...

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Identifiers

PMID: 20975660
DOI: 10.1038/labinvest.2010.179

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