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Article

Expression and somatic mutations of SDHAF2 (SDH5), a novel endocrine tumor suppressor gene in parathyroid tumors of primary hyperparathyroidism.

Endocrine - 1 Dec 2010

Starker Lee F, Delgado-Verdugo Alberto, Udelsman Robert, Björklund Peyman, Carling Tobias

Abstract excerpt

To investigate the SDHAF2 gene and its effect on primary hyperparathyroidism. Parathyroid tumors causing primary hyperparathyroidism (pHPT) are one of the more common endocrine neoplasias. Loss of heterozygosity at chromosome 11q13 is the most common chromosomal aberration in parathyroid tumors o...

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Share to DNA Mutational Analysis
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Share to Gene Expression Regulation, Neoplastic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, Tumor Suppressor

Share to Hyperparathyroidism, Primary

Share to Mitochondrial Proteins

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Source

Identifiers

PMID: 20972721
DOI: 10.1007/s12020-010-9399-0

Genes

SDHAF2
MEN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20972721-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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