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Article

Sipl1 and Rbck1 are novel Eya1-binding proteins with a role in craniofacial development.

Molecular and cellular biology - 1 Dec 2010

Landgraf Kathrin, Bollig Frank, Trowe Mark-Oliver, Besenbeck Birgit, Ebert Christina, Kruspe Dagmar, Kispert Andreas, Hänel Frank, Englert Christoph

Abstract excerpt

The eyes absent 1 protein (Eya1) plays an essential role in the development of various organs in both invertebrates and vertebrates. Mutations in the human EYA1 gene are linked to BOR (branchio-oto-renal) syndrome, characterized by kidney defects, hearing loss, and branchial arch anomalies. For a better understanding of Eya1's function, we have set out to identify new Eya1-interacting proteins. Here we report the...

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Identifiers

PMID: 20956555
DOI: 10.1128/MCB.01645-09
PMCID: PMC3004267

Genes

EYA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Sipl1 and Rbck1 are novel Eya1-binding proteins with a role in craniofacial development.PMID 20956555Read ↗

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