Article
Telomere deficiencies on chromosomes 9p, 15p, 15q and Xp: potential biomarkers for breast cancer risk.
Human molecular genetics - 15 Jan 2011
Zheng Yun-Ling, Zhou Xin, Loffredo Christopher A, Shields Peter G, Sun Bing
Abstract excerpt
Although telomere dysfunction is a characteristic of breast cancer cells, the relationship between deficiency on individual chromosomal telomeres in normal somatic cells and breast cancer risk has not been characterized. A case-control study was conducted to examine the associations between individual lengths of 92 telomeres in the human genome and the risk of breast cancer in 204 newly diagnosed breast cancer...
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