Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Alpha-1-antitrypsin deficiency.

Best practice & research. Clinical gastroenterology - 1 Oct 2010

Bals Robert

Abstract excerpt

Alpha-1-antitrypsin deficiency (AATD) is a rare genetic disorder associated with the development of liver and lung disease. AAT is a 52-kD glycoprotein, produced mainly by hepatocytes and secreted into the blood. Agglomeration of the AAT-protein in hepatocytes can result in liver disease. Exposure to smoke is the major risk factor for the development of lung disease characterised as early chronic obstructive lung...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to alpha 1-Antitrypsin
Share to alpha 1-Antitrypsin Deficiency
Share to Genotype

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Isoelectric Focusing

Share to Liver Diseases

Share to Lung Diseases

Share to Pulmonary Disease, Chronic Obstructive

Source

Identifiers

PMID: 20955965
DOI: 10.1016/j.bpg.2010.08.006

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Alpha-1-antitrypsin deficiency.PMID 20955965Read ↗

Alpha-1 antitrypsin deficiency.Semantic proximity Read ↗

Alpha-1 antitrypsin deficiencySemantic proximity Read ↗

Recent advances in understanding and treating COPD related to α1-antitrypsin deficiency.Semantic proximity Read ↗

Alpha-1-antitrypsin deficiency: Genetic variations, clinical manifestations and therapeutic interventions.Semantic proximity Read ↗

Advances in managing COPD related to α1 -antitrypsin deficiency: An under-recognized genetic disorder.Semantic proximity Read ↗

Alpha-1 antitrypsin deficiency-associated liver disease: From understudied disorder to the poster child of genetic medicine.Semantic proximity Read ↗

Alpha-1 Antitrypsin Deficiency: Current Landscape of Detection, Management, and Treatment.Semantic proximity Read ↗

Role of alpha-1 antitrypsin in human health and disease.Semantic proximity Read ↗

Understanding alpha-1 antitrypsin deficiency: A review with an allergist's outlookSemantic proximity Read ↗

Hereditary alpha-1-antitrypsin deficiency and its clinical consequences.Semantic proximity Read ↗

Alpha-1 antitrypsin deficiency: outstanding questions and future directionsSemantic proximity Read ↗

Historical role of alpha-1-antitrypsin deficiency in respiratory and hepatic complications.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.