Article
Statins alter intracellular calcium homeostasis in malignant hyperthermia susceptible individuals.
Cardiovascular therapeutics - 1 Dec 2010
Metterlein T, Schuster F, Tadda L, Hager M, Roewer N, Anetseder M
Abstract excerpt
AIMS: Statines, HMG-CoA reductase inhibitors, are widely used to treat hypercholesterinemia. These substances are well tolerated, but myotoxic effects have been reported. The exact mechanisms of the induced myotoxicity are unknown but an involvement of intracellular calcium handling is suspected....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
