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Article

One residue substitution in PcyA leads to unexpected changes in tetrapyrrole substrate binding.

Biochemical and biophysical research communications - 12 Nov 2010

Wada Kei, Hagiwara Yoshinori, Yutani Yuko, Fukuyama Keiichi

Abstract excerpt

Phycocyanobilin:ferredoxin oxidoreductase (PcyA) catalyzes the sequential reduction of the vinyl group of the D-ring and A-ring of biliverdin IXα (BV), using reducing equivalents provided by ferredoxin. This reaction produces phycocyanobilin, a pigment used for light-harvesting and light-sensing in red algae and cyanobacteria. The crystal structure of PcyA-BV reveals that BV is specifically bound in the PcyA...

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Identifiers

PMID: 20946883
DOI: 10.1016/j.bbrc.2010.10.037

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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