Article
Use of robotics in high-throughput DNA sequencing.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2011
Keeney Stephen
Abstract excerpt
Until relatively recently, full sequencing of genes consisting of more than several exons was not considered practicable within a routine diagnostic context. As a result, many approaches to unknown mutation detection in a specific gene involved a mutation pre-screening step to limit the amount of DNA sequencing required. Protocols to pre-screen for mutations and limit the amount of DNA sequencing may not localise...
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