Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mass spectrometric-based proteomic analysis of amyloid neuropathy type in nerve tissue.

Archives of neurology - 1 Feb 2011

Klein Christopher J, Vrana Julie A, Theis Jason D, Dyck Peter J, Dyck P James B, Spinner Robert J, Mauermann Michelle L, Bergen H Robert, Zeldenrust Steven R, Dogan Ahmet

Abstract excerpt

OBJECTIVE: To determine the specific type of amyloid from nerve biopsies using laser microdissection (LMD) and mass spectrometric (MS)-based proteomic analysis. DESIGN, SETTING, AND PATIENTS: Twenty-one nerve biopsy specimens (17 sural, 3 sciatic, and 1 root amyloidoma) infiltrated by amyloid were studied. Immunohistochemical subtyping was unable to determine the specific amyloid type for these 21 cases, but the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amyloid Neuropathies
Share to Gelsolin

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunochemistry

Share to Low Density Lipoprotein Receptor-Related Protein-1

Share to Microdissection

Share to Sciatic Nerve

Share to Serum Amyloid P-Component

Share to Sural Nerve

Source

Open in PubMed Open full text

Identifiers

PMID: 20937937
DOI: 10.1001/archneurol.2010.261
PMCID: PMC3167172

Genes

TTR
GSN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mass spectrometric-based proteomic analysis of amyloid neuropathy type in nerve tissue.PMID 20937937Read ↗

Mass Spectrometry Amyloid Typing Is Reproducible across Multiple Organ SitesSemantic proximity Read ↗

Clinical diagnosis and typing of systemic amyloidosis in subcutaneous fat aspirates by mass spectrometry-based proteomics.Semantic proximity Read ↗

Laser microdissection and mass spectrometry–based proteomics aids the diagnosis and typing of renal amyloidosisSemantic proximity Read ↗

Renal amyloidosis associated with a novel sequence variant of gelsolin.Semantic proximity Read ↗

Assessing the Consistency of Mass Spectrometry, a Clinical-Laboratory Model, and Immunohistochemistry in Amyloid Subtyping: A Brazilian ExperienceSemantic proximity Read ↗

New insights into systemic amyloidosis: the importance of diagnosis of specific type.Semantic proximity Read ↗

Identification of transthyretin variants by sequential proteomic and genomic analysis.Semantic proximity Read ↗

Immunohistochemical characterization of amyloid proteins in sural nerves and clinical associations in amyloid neuropathy.Semantic proximity Read ↗

Serum Proteomic Variability Associated with Clinical Phenotype in Familial Transthyretin Amyloidosis (ATTRm).Semantic proximity Read ↗

Cutaneous nerve biomarkers in transthyretin familial amyloid polyneuropathy.Semantic proximity Read ↗

The neuromuscular manifestations of amyloidosis.Semantic proximity Read ↗

Fibrinogen alpha amyloidosis: insights from proteomicsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.