Article
Flavonoids and genomic instability induced by ionizing radiation.
Drug discovery today - 1 Nov 2010
Hosseinimehr Seyed Jalal
Abstract excerpt
DNA is the cellular target that has the most damage induced by ionizing radiation (IR). If genomic instability resulting from this DNA damage is not correctly repaired, it leads to mutation, cancer and cell death. Flavonoids are a family of natural products that affect oxidative stress and enhance genomic stability through DNA interaction. Although flavonoids exert protective effects against IR in normal cells,...
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