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Article

Higher serum sTNFR1 level predicts conversion from mild cognitive impairment to Alzheimer's disease.

Journal of Alzheimer's disease : JAD - 1 Jan 2010

Diniz Breno Satler, Teixeira Antonio Lucio, Ojopi Elida Benquique, Talib Leda Leme, Mendonça Vanessa Amaral, Gattaz Wagner Farid, Forlenza Orestes Vicente

Abstract excerpt

The activation of inflammatory cascades has been consistently demonstrated in the pathophysiology of Alzheimer's disease (AD). Among several putative neuroinflammatory mechanisms, the tumor necrosis factor α (TNF-α) signaling system has a central role in this process. Recent evidence indicates that the abnormal production of inflammatory factors may accompany the progression from mild cognitive impairment (MCI)...

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Identifiers

PMID: 20930310
DOI: 10.3233/JAD-2010-100921

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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