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Article

Evidence for heterozygous abnormalities of the elastin gene (ELN) affecting the quantity of vocal fold elastic fibers: a pilot study.

Journal of voice : official journal of the Voice Foundation - 1 Mar 2011

Watts Christopher R, Knutsen Russell H, Ciliberto Christopher, Mecham Robert P

Abstract excerpt

OBJECTIVES: To investigate the effects of a heterozygous elastin gene (Eln) abnormality (deletion of one Eln allele) on the structural characteristics of the vocal fold lamina propria using a mouse model of human disease. STUDY DESIGN: Cross-sectional between-subjects design. METHODS: Five mice, four with heterozygous Eln deletions (Eln +/-) serving as an animal model for the human disease supravalvular aortic...

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Source

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Identifiers

PMID: 20926252
DOI: 10.1016/j.jvoice.2010.04.006
PMCID: PMC3765004

Genes

ELN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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