Article
[Pathogenesis of liver disease in alpha 1-antitrypsin deficiency].
Acta medica Austriaca - 1 Jan 1990
Vogel W, Braunsteiner T, Dietze O, Braunsteiner H
Abstract excerpt
Alpha-1-antitrypsin deficiency (A1ATD) is one of the most common lethal hereditary disorders. Approximately 5 to 10% of the general population carry an "at risk" gene for the development of liver disease or emphysema of the lung. Patients with A1ATD associated liver disease constitute a histologically and clinically heterogeneous group. The pathogenesis of the disease still remains to be elucidated. Recent...
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