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Article

Use of a heterotopic cardiac isotransplant for pharmacological and toxicological studies.

Toxicologic pathology - 1 Jan 1990

Korecky B, Masika M

Abstract excerpt

The heterotopically transplanted rat heart provides a unique model for examination of the direct humoral effects on the myocardium since the transplanted heart is exposed to the same hormonal milieu as the in situ heart but does not support the hemodynamic load. In this model, the heart of an inbred rat is transplanted into the abdomen of a recipient of the same inbred strain by attaching the stumps of aorta and...

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PMID: 2091232

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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