Article
Use of a heterotopic cardiac isotransplant for pharmacological and toxicological studies.
Toxicologic pathology - 1 Jan 1990
Korecky B, Masika M
Abstract excerpt
The heterotopically transplanted rat heart provides a unique model for examination of the direct humoral effects on the myocardium since the transplanted heart is exposed to the same hormonal milieu as the in situ heart but does not support the hemodynamic load. In this model, the heart of an inb...
Topics
- Animals
- Heart
- Heart Transplantation
- Hemodynamics
- Models, Cardiovascular
- Myocardium
- Phenotype
- Physical Exertion
- Rats
- Thyroid Hormones
- Toxicology
- Transplantation, Heterotopic