Molecular analysis of gene rearrangements and mutations in acute leukemias and myeloproliferative neoplasms.

Abstract excerpt

A large subset of acute leukemias and other myeloproliferative neoplasms contain specific genetic alterations, many of which are associated with unique clinical and pathologic features. These alterations include chromosomal translocations leading to oncogenic fusion genes, as well as mutations leading to aberrant activation of a variety of proteins critical to hematopoietic progenitor cell proliferation and...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Acute Disease
• Share to Cell Differentiation
• Share to Cell Proliferation