Article
Nucleotide polymorphisms and the 5'-UTR transcriptional analysis of the bovine growth hormone secretagogue receptor 1a (GHSR1a) gene.
Animal science journal = Nihon chikusan Gakkaiho - 1 Oct 2010
Komatsu Masanori, Fujimori Yuki, Sato Yoichi, Okamura Hiroaki, Sasaki Seiki, Itoh Tomohito, Morita Mitsuo, Nakamura Ryoichi, Oe Toshiaki, Furuta Masako, Yasuda Junpei, Kojima Takatoshi, Watanabe Toshio, Hayashi Takeshi, Malau-Aduli Aduli E O, Takahashi Hideaki
Abstract excerpt
Growth hormone secretagogue receptor 1a (GHSR1a) mediates the different actions of its endogenous ligand, ghrelin. Ghrelin-GHSR is involved in many important functions that include growth hormone secretion and food intake. We evaluated the haplotype variety and characterized the microsatellite ((TG)(n) , 5'-UTR) and nucleotide polymorphisms of the bovine GHSR1a gene. The nucleotide sequencing of this gene (∼6 kb)...
Topics
- 5' Untranslated Regions
- Animals
- Cattle
- Polymorphism, Genetic
- Polymorphism, Single Nucleotide
- Receptors, Ghrelin
- Transcription, Genetic